Associate Director, Clinical Pharmacology

Overview The Associate Director, Clinical Pharmacology supports a rapidly expanding clinical portfolio of RNAi therapeutics within the CNS franchise. This role provides clinical pharmacology expertise across clinical-stage programs, with a strong focus on pharmacokinetics (PK), pharmacodynamics (PD), and PK/PD analyses to inform clinical development and regulatory decision-making. The position requires strong scientific expertise, critical thinking, and the ability to independently interpret and integrate complex clinical pharmacology data within a highly matrixed environment. The Associate Director partners closely with Research, Clinical Development, Bioanalytical, Regulatory, Project Management, and other R&D functions, contributing to clinical study design, data analysis, regulatory submissions, and scientific publications in support of advancing innovative RNAi therapies. This is a virtual role based in The Netherlands or UK. Key Responsibilities Represent independently Clinical Pharmacology and provide clinical pharmacology support and guidance to clinical stage project teams. Lead the analysis, interpretation, integration and reporting of clinical pharmacology data Conduct PK and PK/PD analyses to guide clinical development decisions Provide clinical pharmacology input for regulatory submissions such as briefing documents, IND, CTA and NDA Prepare and input independently appropriate documents or sections of clinical protocols, Investigator Brochures, Clinical Study