Associate Director / Director of Product Management, Signatera Hematologic Oncol
Full-time
US
Nov 6, 2026
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About the Role
Position Summary: Natera is a global leader in cell-free DNA testing, focused on changing the management of disease in reproductive health, oncology, and organ transplantation. Signatera is a personalized, tumor-informed test for molecular residual disease (MRD) assessment and surveillance monitoring in patients previously diagnosed with cancer. The Associate Director / Director of Product Management, Signatera Heme will own the product strategy and roadmap for Signatera in hematologic malignancies, starting with multiple myeloma and lymphomas. This person will work in a highly matrixed environment with the Foresight BU, R&D, Lab Operations, Software Engineering, Medical Affairs, Marketing, Business Development, and Regulatory. The role combines product management, market entry as a laboratory developed test (LDT), evidence generation, analytics, and clinical trial product support, including trials run under IUO and IVD pathways. Primary Responsibilities: Develop and execute the Signatera product roadmap for hematologic malignancies, beginning with multiple myeloma and lymphomas (for example, DLBCL, follicular, mantle cell, and Hodgkin lymphoma) and extending to additional heme indications. Lead market entry planning for Signatera in heme as a laboratory developed test (LDT), including clinical validation requirements, CLIA and state requirements, market access/reimbursement and payer considerations, and launch readiness with Lab Operations, Regulatory, Medical, commercia