Clinical Development Leader, Lifecycle Management

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed. The Opportunity Turning scientific possibilities into meaningful opportunities for patients takes more than expertise. It takes breadth, sound judgment, and the drive to lead across programs, translating emerging data into decisions that move medicines forward.At Praxis, you’ll provide clinical leadership across lifecycle management activities and early-phase development throughout our pipeline. You’ll work across mechanisms, indications, and stages of development: shaping opportunities, leading early clinical work, interpreting emerging data, and turning scientific and clinical insights into development decisions.This is a role for someone who leads the work, not someone who primarily advises or reviews it. You’ll bring the breadth to move confidently across programs and the judgment to identify where clinical development can create the greatest value for patients. Primary Responsibilities Lifecycle strategy: Identify and drive opportunities to expand the impact of late-stage and marketed assets, including new indications, label expansion, and formulation opportunities. Early development: Lead first-in-human and dose-escalation studies, applying PK/PD and emerging clinical data to dose selection, decision rules, and next-stage development. Clinical entry: Drive the clinical strategy and content for IND-enabling submissions and the decisions required to move pr