Information System Security Officer (ISSO)

Information System Security Officer (ISSO) Position Summary We are seeking an experienced Information System Security Officer (ISSO) to provide cybersecurity, risk management, and information assurance support for a large-scale federal healthcare technology program. The ISSO will work closely with system owners, security leadership, technical teams, developers, and program stakeholders to ensure information systems maintain appropriate security controls and comply with applicable federal cybersecurity requirements throughout the system lifecycle. This role will support security authorization activities, continuous monitoring, risk assessments, vulnerability management, security documentation, and remediation efforts for complex enterprise systems. Key Responsibilities Serve as an ISSO for assigned federal information systems and applications. Support implementation and ongoing assessment of security controls in accordance with applicable federal cybersecurity requirements. Support the Risk Management Framework (RMF) throughout the system development and operational lifecycle. Develop, maintain, and review system security documentation and authorization artifacts. Support Assessment and Authorization (A&A) and Authority to Operate (ATO) Maintain and update System Security Plans (SSPs), Plans of Action and Milestones (POA&Ms), risk assessments, and related security documentation. Track security vulnerabilities, findings, remediation activities, and corrective actions. C