Senior Principal Scientist, US Regulatory Innovation

Welcome to Dechra Dechra is an international veterinary pharmaceutical business focused on specialty products. We develop, manufacture, sell and market high-quality products exclusively for veterinarians around the world. Job Purpose The Regulatory Affairs Senior Principal Scientist leads and delivers thoughtful, forward-looking regulatory strategies for the clinical safety and efficacy of traditional small-molecule drugs and large-molecule biotherapeutics, including monoclonal antibodies and other complex biologics, in the US. This role identifies regulatory opportunities and risks early, develops strategic options and helps ensure regulatory pathways support successful and timely product development across all US programs. The role may also represent Global RA on project teams and work with regional RA teams to support a global registration strategy. In addition, the Senior Principal Scientist mentors junior members of the US Innovation Regulatory Affairs team, helping them build technical regulatory skills in clinical safety and efficacy. Key Responsibilities Develop, lead, and deliver innovative, risk‑based regulatory strategies for drugs and biotherapeutics (e.g., monoclonal antibodies, protein therapeutics). Identify regulatory risks and opportunities early and develop strategic options to address or make the most of them throughout the development lifecycle. Provide scientific and regulatory guidance to cross‑functional project teams, supporting strategic decisions, re